2014International Journal of Infectious DiseasesOpen access

Tigecycline for severe Clostridium difficile infection

Ashley Thomas, Farhan Anwar Khan, Nizam Uddin, Mark R. Wallace

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Abstract

Limited data suggest that tigecycline may be of value in the treatment of Clostridiumdifficile infection. We reviewed our experience using tigecycline to treat severe c. difficile and compared outcomes to similarly ill patients who did not receive tigecycline. We found no difference between the groups. Further study is needed before tigecycline can be recommended for use in severe C. difficile infection.

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What this paper is about

Limited data suggest that tigecycline may be of value in the treatment of Clostridiumdifficile infection. We reviewed our experience using tigecycline to treat severe c. difficile and compared outcomes to similarly ill patients who did not receive tigecycline. We found no difference between the groups. Further study is needed before tigecycline can be recommended for use in severe C. difficile infection.

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Available abstract

Limited data suggest that tigecycline may be of value in the treatment of Clostridiumdifficile infection. We reviewed our experience using tigecycline to treat severe c. difficile and compared outcomes to similarly ill patients who did not receive tigecycline. We found no difference between the groups. Further study is needed before tigecycline can be recommended for use in severe C. difficile infection.

Key concepts: Tigecycline, Clostridium difficile, Medicine, Intensive care medicine, Internal medicine, Antibiotics, Microbiology, Biology

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