Xanthone and Flavonoid Constituents ofGarcinia dulcis(Guttiferae)
Leslie J. Harrison, Lup-San Leong, Yuan-Wah Leong, Guat-Lee Sia, Keng‐Yeow Sim, Hugh Tiang Wah Tan
Abstract
Leslie J. Harrison, Lup-San Leong, Yuan-Wah Leong, Guat-Lee Sia, Keng‐Yeow Sim, Hugh Tiang Wah Tan
Abstract
Extraction of the branches of Garcinia dulcis afforded a xanthone with a novel oxygenation pattern [1,4,6-trihydroxy-5-methoxy-7-(3-methylbut-2-enyl)xanthone] in addition to the triterpenoid friedelin and the known flavonoids 3′-(3-methylbut-2-enyl)naringenin, I3,II8-biapigenin and podocarpusflavoneA. The structures were determined by a combination of 2D homo- and heteronuclear NMR correlation spectroscopy and NOE difference spectroscopy.
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Extraction of the branches of Garcinia dulcis afforded a xanthone with a novel oxygenation pattern [1,4,6-trihydroxy-5-methoxy-7-(3-methylbut-2-enyl)xanthone] in addition to the triterpenoid friedelin and the known flavonoids 3′-(3-methylbut-2-enyl)naringenin, I3,II8-biapigenin and podocarpusflavoneA. The structures were determined by a combination of 2D homo- and heteronuclear NMR correlation spectroscopy and NOE difference spectroscopy.
Key concepts: Xanthone, Friedelin, Chemistry, Naringenin, Flavonoid, Garcinia, Heteronuclear molecule, Mangiferin