1995Journal of Toxicology Clinical ToxicologyRequires access

Prolonged Neuromuscular Blockade when Mivacurium and Pancuronium Were Administered in Series

Zvi Herschman, Cristina G. Pamaar

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Abstract

Long acting non-depolarizing neuromuscular blockade is useful in many clinical circumstances, especially during surgical procedures. Reinstitution of the blockade for short periods to facilitate the completion of clinical tasks can be accomplished in different ways. We present a case wherein a short-acting non-depolarizing neuromuscular blocker used after a long-acting one resulted in an unusual prolongation of the neuromuscular blockade.

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What this paper is about

Long acting non-depolarizing neuromuscular blockade is useful in many clinical circumstances, especially during surgical procedures. Reinstitution of the blockade for short periods to facilitate the completion of clinical tasks can be accomplished in different ways. We present a case wherein a short-acting non-depolarizing neuromuscular blocker used after a long-acting one resulted in an unusual prolongation of the neuromuscular blockade.

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Available abstract

Long acting non-depolarizing neuromuscular blockade is useful in many clinical circumstances, especially during surgical procedures. Reinstitution of the blockade for short periods to facilitate the completion of clinical tasks can be accomplished in different ways. We present a case wherein a short-acting non-depolarizing neuromuscular blocker used after a long-acting one resulted in an unusual prolongation of the neuromuscular blockade.

Key concepts: Neuromuscular Blockade, Blockade, Medicine, Neuromuscular Blocking Agents, Anesthesia, Neuromuscular junction, Neuromuscular transmission, Internal medicine

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