Laboratory evaluation of the anticoagulants coumatetralyl and brodifacoum againstRattus argentiventerin Peninsular Malaysia1
A. P. Buckle, F. P. Rowe, Abdul Rahman Husin
Abstract
A. P. Buckle, F. P. Rowe, Abdul Rahman Husin
Abstract
In laboratory toxicity tests using individually‐caged rice field rats, Rattus argentiventer (Robinson & Klossl, complete mortality occurred when the rats were fed on broken rice/corn oil bait containing 0.0375% coumatetralyl for four days. Equivalent kills were obtained when rats we're fed 0.002% and 0.005% brodifacoum for one day. Both compounds were more toxic than warfarin at 0.025%. Choice tests showed that 0.001% and 0.0005% brodifacoum were as acceptable as 0.025% warfarin, but higher concentrations and 0.005% and 0.0375% coumatetralyl were poorly accepted. The potential advantages of coumatetralyl and brodifacoum over other rodenticides for the control of R. argentiventer in rice fields in Malaysia are discussed.
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In laboratory toxicity tests using individually‐caged rice field rats, Rattus argentiventer (Robinson & Klossl, complete mortality occurred when the rats were fed on broken rice/corn oil bait containing 0.0375% coumatetralyl for four days. Equivalent kills were obtained when rats we're fed 0.002% and 0.005% brodifacoum for one day. Both compounds were more toxic than warfarin at 0.025%. Choice tests showed that 0.001% and 0.0005% brodifacoum were as acceptable as 0.025% warfarin, but higher concentrations and 0.005% and 0.0375% coumatetralyl were poorly accepted. The potential advantages of coumatetralyl and brodifacoum over other rodenticides for the control of R. argentiventer in rice fields in Malaysia are discussed.
Key concepts: Brodifacoum, Rodenticide, Warfarin, Toxicology, Corn oil, Paddy field, Biology, Veterinary medicine