2006•Seibutsu ButsuriOpen access
A Novel DNA Repair Promoting Protein from the Radioresistant Bacterium
Katsuya Satoh, Hirofumi Ohba, Issay Narumi
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Abstract
The radioresistant bacterium Deinococcus radiodurans possesses the efficient repair capacity to DNA double strand breaks. By analyzing the DNA damage repair-deficient mutant, a novel DNA repair promoting protein PprA that plays a critical role in the radiation resistance was identified. Here we review our current understanding of DNA repair and radiation response mechanisms around PprA protein.
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