2010•OphthalmologicaRequires access

Detection of Varicella-Zoster Virus DNA in Conjunctivas of Patients with Herpes Zoster

Takahiro Tamura, Masami Yoshida, Tadashi Tezuka

Abstract

Detection of varicella-zoster virus (VZV) DNA was carried out in the conjunctivas of 18 patients with herpes zoster by polymerase chain reaction. The rate of VZV DNA detection in conjunctivas was 3/4 in herpes zoster ophthalmicus associated with eruption on the dorsum nasi, 2/5 in herpes zoster ophthalmicus without eruption on the dorsum nasi, 1/2 in herpes zoster with eruption on the cheek and lower jaw, 1/2 in generalized herpes zoster and 0/5 in herpes zoster associated with eruption on the trunk or extremities, respectively. The reason for the detection of VZV DNA in conjunctivas is discussed.

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Key concepts: Herpes Zoster Ophthalmicus, Varicella zoster virus, Virology, Medicine, Virus, Herpesviridae, Dorsum, Alphaherpesvirinae