2000•Journal of Laboratory and Clinical MedicineRequires access

3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts

Akira Honda, Gerald Salen, Megumi Honda, ASHOK KUMAR BATTA, G S Tint, Guorong Xu, Thomas S. Chen, Naomi Tanaka, Sarah Shefer

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Key concepts: Reductase, HMG-CoA reductase, Hydroxymethylglutaryl-CoA reductase, Coenzyme A, Cholesterol, Sterol, 7-Dehydrocholesterol reductase, Enzyme

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts — Research Paper | ScholarLens