1974FEBS LettersOpen access

Inhibition of creatine kinase by creatinine phosphate

G. Gercken, Volker Döring

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Abstract

Creatinine phosphate was shown to be no substrate of purified creatine kinase from skeletal muscle or of creatine kinase in heart muscle homogenate. It was found to be a competitive inhibitor with respect to creatine phosphate and a noncompetitive inhibitor with respect to ADP.

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Creatinine phosphate was shown to be no substrate of purified creatine kinase from skeletal muscle or of creatine kinase in heart muscle homogenate. It was found to be a competitive inhibitor with respect to creatine phosphate and a noncompetitive inhibitor with respect to ADP.

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Available abstract

Creatinine phosphate was shown to be no substrate of purified creatine kinase from skeletal muscle or of creatine kinase in heart muscle homogenate. It was found to be a competitive inhibitor with respect to creatine phosphate and a noncompetitive inhibitor with respect to ADP.

Key concepts: Creatine, Creatine kinase, Phosphate, Creatinine, Substrate (aquarium), Chemistry, Biochemistry, Internal medicine

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