2007Annals of Internal MedicineRequires access

Alternative Treatments of Vasomotor Symptoms of Menopause

Jonathan R. Byron

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Abstract

Letters4 September 2007Alternative Treatments of Vasomotor Symptoms of MenopauseJonathan R. Byron, PhDJonathan R. Byron, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-147-5-200709040-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The dosages used in Newton and colleagues' study (1)—160 mg/d of black cohosh root or 200 mg/d of black cohosh and other botanicals—are much lower than those taken by many women. Some commonly used supplements contain 500 mg or more of Cimicifuga racemosa root per capsule, and multiple capsules are taken per day. A daily dose that is 10 times larger than that used in the experiment is not unusual. Assuming that there is a dose dependency to previously demonstrated phytoestrogen properties of black cohosh, it is unfortunate that Newton and colleagues' study only looked at relatively ...Reference1. Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med. 2006;145:869-79. [PMID: 17179056] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTreatment of Vasomotor Symptoms of Menopause with Black Cohosh, Multibotanicals, Soy, Hormone Therapy, or Placebo Katherine M. Newton , Susan D. Reed , Andrea Z. LaCroix , Louis C. Grothaus , Kelly Ehrlich , and Jane Guiltinan Alternative Treatments of Vasomotor Symptoms of Menopause Katherine M. Newton , Susan D. Reed , and Andrea Z. LaCroix Alternative Treatments of Vasomotor Symptoms of Menopause Jonathan P. Krueger Alternative Treatments of Vasomotor Symptoms of Menopause Baoming Ge Metrics Cited byTwo new triterpenoid-chromone hybrids from the rhizomes of Actaea cimicifuga L. (syn. Cimicifuga foetida L.) and their cytotoxic activitiesHypericum perforatum L. preparations for menopause: a meta-analysis of efficacy and safety 4 September 2007Volume 147, Issue 5Page: 346-347KeywordsConflicts of interestMenopauseResearch design ePublished: 4 September 2007 Issue Published: 4 September 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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Letters4 September 2007Alternative Treatments of Vasomotor Symptoms of MenopauseJonathan R. Byron, PhDJonathan R. Byron, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-147-5-200709040-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The dosages used in Newton and colleagues' study (1)—160 mg/d of black cohosh root or 200 mg/d of black cohosh and other botanicals—are much lower than those taken by many women. Some commonly used supplements contain 500 mg or more of Cimicifuga racemosa root per capsule, and multiple capsules are taken per day. A daily dose that is 10 times larger than that used in the experiment is not unusual. Assuming that there is a dose dependency to previously demonstrated phytoestrogen properties of black cohosh, it is unfortunate that Newton and colleagues' study only looked at relatively ...Reference1. Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med. 2006;145:869-79. [PMID: 17179056] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTreatment of Vasomotor Symptoms of Menopause with Black Cohosh, Multibotanicals, Soy, Hormone Therapy, or Placebo Katherine M. Newton , Susan D. Reed , Andrea Z. LaCroix , Louis C. Grothaus , Kelly Ehrlich , and Jane Guiltinan Alternative Treatments of Vasomotor Symptoms of Menopause Katherine M. Newton , Susan D. Reed , and Andrea Z. LaCroix Alternative Treatments of Vasomotor Symptoms of Menopause Jonathan P. Krueger Alternative Treatments of Vasomotor Symptoms of Menopause Baoming Ge Metrics Cited byTwo new triterpenoid-chromone hybrids from the rhizomes of Actaea cimicifuga L. (syn. Cimicifuga foetida L.) and their cytotoxic activitiesHypericum perforatum L. preparations for menopause: a meta-analysis of efficacy and safety 4 September 2007Volume 147, Issue 5Page: 346-347KeywordsConflicts of interestMenopauseResearch design ePublished: 4 September 2007 Issue Published: 4 September 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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Letters4 September 2007Alternative Treatments of Vasomotor Symptoms of MenopauseJonathan R. Byron, PhDJonathan R. Byron, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-147-5-200709040-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The dosages used in Newton and colleagues' study (1)—160 mg/d of black cohosh root or 200 mg/d of black cohosh and other botanicals—are much lower than those taken by many women. Some commonly used supplements contain 500 mg or more of Cimicifuga racemosa root per capsule, and multiple capsules are taken per day. A daily dose that is 10 times larger than that used in the experiment is not unusual. Assuming that there is a dose dependency to previously demonstrated phytoestrogen properties of black cohosh, it is unfortunate that Newton and colleagues' study only looked at relatively ...Reference1. Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med. 2006;145:869-79. [PMID: 17179056] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTreatment of Vasomotor Symptoms of Menopause with Black Cohosh, Multibotanicals, Soy, Hormone Therapy, or Placebo Katherine M. Newton , Susan D. Reed , Andrea Z. LaCroix , Louis C. Grothaus , Kelly Ehrlich , and Jane Guiltinan Alternative Treatments of Vasomotor Symptoms of Menopause Katherine M. Newton , Susan D. Reed , and Andrea Z. LaCroix Alternative Treatments of Vasomotor Symptoms of Menopause Jonathan P. Krueger Alternative Treatments of Vasomotor Symptoms of Menopause Baoming Ge Metrics Cited byTwo new triterpenoid-chromone hybrids from the rhizomes of Actaea cimicifuga L. (syn. Cimicifuga foetida L.) and their cytotoxic activitiesHypericum perforatum L. preparations for menopause: a meta-analysis of efficacy and safety 4 September 2007Volume 147, Issue 5Page: 346-347KeywordsConflicts of interestMenopauseResearch design ePublished: 4 September 2007 Issue Published: 4 September 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Key concepts: Black cohosh, Medicine, Vasomotor, Menopause, Placebo, Traditional medicine, Internal medicine, Alternative medicine

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