1995Birkhäuser Basel eBooksRequires access

GABA Receptors: Recent Advances

Norman G. Bowery, Kengo Kuriyama, Jeremy J. Lambert, R W Olsen, T.G. Smart

Open publisher page 2 citations

Abstract

It is now nearly three decades since the full significance of GABA as an inhibitory neurotransmitter was first established [1]. However, it is only for about the last 10 years that we have known that the actions of GABA are mediated via multiple receptor subtypes, rather than a single one [2]. Broadly the receptor-mediated effects of GABA can be classified as fast or slow with the former relating to the GABAA receptor class and the latter to the GABAB class [3]. Further functional receptor types e.g. GABAC may well become established in future as Johnston recently suggested [4] but for the purpose of this review, the material has been confined to GABAA and GABAB.

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What this paper is about

It is now nearly three decades since the full significance of GABA as an inhibitory neurotransmitter was first established [1]. However, it is only for about the last 10 years that we have known that the actions of GABA are mediated via multiple receptor subtypes, rather than a single one [2]. Broadly the receptor-mediated effects of GABA can be classified as fast or slow with the former relating to the GABAA receptor class and the latter to the GABAB class [3]. Further functional receptor types e.g. GABAC may well become established in future as Johnston recently suggested [4] but for the purpose of this review, the material has been confined to GABAA and GABAB.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

It is now nearly three decades since the full significance of GABA as an inhibitory neurotransmitter was first established [1]. However, it is only for about the last 10 years that we have known that the actions of GABA are mediated via multiple receptor subtypes, rather than a single one [2]. Broadly the receptor-mediated effects of GABA can be classified as fast or slow with the former relating to the GABAA receptor class and the latter to the GABAB class [3]. Further functional receptor types e.g. GABAC may well become established in future as Johnston recently suggested [4] but for the purpose of this review, the material has been confined to GABAA and GABAB.

Key concepts: GABAB receptor, GABAA receptor, GABAA-rho receptor, Neuroscience, Receptor, Inhibitory postsynaptic potential, GABA receptor, Neurotransmitter

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