GABA Receptors: Recent Advances
Norman G. Bowery, Kengo Kuriyama, Jeremy J. Lambert, R W Olsen, T.G. Smart
Abstract
Norman G. Bowery, Kengo Kuriyama, Jeremy J. Lambert, R W Olsen, T.G. Smart
Abstract
It is now nearly three decades since the full significance of GABA as an inhibitory neurotransmitter was first established [1]. However, it is only for about the last 10 years that we have known that the actions of GABA are mediated via multiple receptor subtypes, rather than a single one [2]. Broadly the receptor-mediated effects of GABA can be classified as fast or slow with the former relating to the GABAA receptor class and the latter to the GABAB class [3]. Further functional receptor types e.g. GABAC may well become established in future as Johnston recently suggested [4] but for the purpose of this review, the material has been confined to GABAA and GABAB.
OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
It is now nearly three decades since the full significance of GABA as an inhibitory neurotransmitter was first established [1]. However, it is only for about the last 10 years that we have known that the actions of GABA are mediated via multiple receptor subtypes, rather than a single one [2]. Broadly the receptor-mediated effects of GABA can be classified as fast or slow with the former relating to the GABAA receptor class and the latter to the GABAB class [3]. Further functional receptor types e.g. GABAC may well become established in future as Johnston recently suggested [4] but for the purpose of this review, the material has been confined to GABAA and GABAB.
Key concepts: GABAB receptor, GABAA receptor, GABAA-rho receptor, Neuroscience, Receptor, Inhibitory postsynaptic potential, GABA receptor, Neurotransmitter