P01-031 – Anakinra for colchicine resistant FMF
Ilan Ben‐Zvi, OL Kukuy, Merav Lidar, Olga Feld, Oleg Perski, Shaye Kivity, Pnina Langevitz, B Pistrom, Avi Livneh
Abstract
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Ilan Ben‐Zvi, OL Kukuy, Merav Lidar, Olga Feld, Oleg Perski, Shaye Kivity, Pnina Langevitz, B Pistrom, Avi Livneh
Abstract
Open-access reader
About 10-20% of Familial Mediterranean Fever (FMF) patients do not achieve complete remission, due to colchicine resistance or sensitivity. Disease control in these patients is still an unmet challenge. Case reports and a small case control study, suggest a role for interleukin 1 beta blockage, particularly anakinra, in the management of this limitation of colchicines.
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About 10-20% of Familial Mediterranean Fever (FMF) patients do not achieve complete remission, due to colchicine resistance or sensitivity. Disease control in these patients is still an unmet challenge. Case reports and a small case control study, suggest a role for interleukin 1 beta blockage, particularly anakinra, in the management of this limitation of colchicines.
Key concepts: Anakinra, Familial Mediterranean fever, Colchicine, Medicine, Rheumatology, Internal medicine, Disease, Gastroenterology