BMP-7 counteracts TGF-β1–induced epithelial-to-mesenchymal transition and reverses chronic renal injury
Michael Zeisberg, Jun‐ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David M. Charytan, Frank M. Strutz, Raghu K. Kalluri
Abstract
Michael Zeisberg, Jun‐ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David M. Charytan, Frank M. Strutz, Raghu K. Kalluri
Abstract
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Key concepts: Epithelial–mesenchymal transition, Transforming growth factor, SMAD, Bone morphogenetic protein 7, Renal stem cell, Mesenchyme, Bone morphogenetic protein, Cancer research