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Characterization of a New Human Diploid Cell Strain, IMR-90

Warren W. Nichols, D. G. Murphy, Vincent J. Cristofalo, Lorraine H. Toji, A.E. Greene, Selena Dwight

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Abstract

A new human diploid fibroblast-like cell line has been established from lung tissue of a female fetus. This has been frozen away in large quantity and characterized for use in research and related purposes. This is the first of a planned series of human cell lines to be established, characterized, and banked in large quantity in support of the National Institute on Aging research and general cell biology.

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What this paper is about

A new human diploid fibroblast-like cell line has been established from lung tissue of a female fetus. This has been frozen away in large quantity and characterized for use in research and related purposes. This is the first of a planned series of human cell lines to be established, characterized, and banked in large quantity in support of the National Institute on Aging research and general cell biology.

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OpenAlex reports 373 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A new human diploid fibroblast-like cell line has been established from lung tissue of a female fetus. This has been frozen away in large quantity and characterized for use in research and related purposes. This is the first of a planned series of human cell lines to be established, characterized, and banked in large quantity in support of the National Institute on Aging research and general cell biology.

Key concepts: Ploidy, WI-38, Fibroblast, Strain (injury), Cell culture, Human lung, Cell, Biology

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