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Comparison of Various Precipitin Tests in the Detection of α-Fetoprotein in Serum

Megumi Nishioka, K. Okita, Yoshiaki Okamoto, Tetsuro Kodama, T Fujita

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Abstract

The Ouchterlony technique, single radial immunodiffusion and fluoro-electro-immunodiffusion (FEID) for the detection of α-fetoprotein (AFP) had their own merits. FEID was at least 30 times as sensitive as the Ouchterlony technique for the detection of serum AFP. Its great sensitivity elicited a positive reaction in sera which were previously negative by the Ouchterlony technique.

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What this paper is about

The Ouchterlony technique, single radial immunodiffusion and fluoro-electro-immunodiffusion (FEID) for the detection of α-fetoprotein (AFP) had their own merits. FEID was at least 30 times as sensitive as the Ouchterlony technique for the detection of serum AFP. Its great sensitivity elicited a positive reaction in sera which were previously negative by the Ouchterlony technique.

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OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The Ouchterlony technique, single radial immunodiffusion and fluoro-electro-immunodiffusion (FEID) for the detection of α-fetoprotein (AFP) had their own merits. FEID was at least 30 times as sensitive as the Ouchterlony technique for the detection of serum AFP. Its great sensitivity elicited a positive reaction in sera which were previously negative by the Ouchterlony technique.

Key concepts: Ouchterlony double immunodiffusion, Precipitin, Immunodiffusion, Radial immunodiffusion, Chemistry, Molecular biology, Biology, Immunology

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