Proposed Two-molecule Intercalation between Neighboring Base Pairs of DNA
Hideyuki Tomosaka, Kentaro Anzai, Saburo Omata
Abstract
Hideyuki Tomosaka, Kentaro Anzai, Saburo Omata
Abstract
DNA intercalation of 9-aminoacridine and its derivatives was evaluated by the UV -VIS absorption-Scatchard plot technique, and it was suggested that two molecules of 9-amino-2,7-dibromoacridine were located between neighboring base pairs of DNA.
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DNA intercalation of 9-aminoacridine and its derivatives was evaluated by the UV -VIS absorption-Scatchard plot technique, and it was suggested that two molecules of 9-amino-2,7-dibromoacridine were located between neighboring base pairs of DNA.
Key concepts: Intercalation (chemistry), DNA, Base pair, Molecule, Base (topology), Chemistry, Scatchard plot, Crystallography