Myelofibrosis and Pancytopenia in Systemic Lupus Erythematosus
El Mouzan, Mirghani A.M Ahmad, Mohamed Al Fadel Saleh, M.O. Al Sohaibani, Yusuf M Al Gindan
Abstract
El Mouzan, Mirghani A.M Ahmad, Mohamed Al Fadel Saleh, M.O. Al Sohaibani, Yusuf M Al Gindan
Abstract
A 13-year-old Saudi girl presented with severe clinical features of systemic lupus erythematosus of 3 months' duration. In addition to laboratory evidence of the disease, the patient was found to have pancytopenia and myelofibrosis. While pancytopenia was considerably improved by steroids, myelofibrosis was not reversed. The coexistence of myelofibrosis and pancytopenia in patients with systemic lupus erythematosus has been reported, but their possible causal relationship remains unresolved.
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A 13-year-old Saudi girl presented with severe clinical features of systemic lupus erythematosus of 3 months' duration. In addition to laboratory evidence of the disease, the patient was found to have pancytopenia and myelofibrosis. While pancytopenia was considerably improved by steroids, myelofibrosis was not reversed. The coexistence of myelofibrosis and pancytopenia in patients with systemic lupus erythematosus has been reported, but their possible causal relationship remains unresolved.
Key concepts: Pancytopenia, Myelofibrosis, Medicine, Immunology, Lupus erythematosus, Dermatology, Bone marrow, Antibody