2006•Expert Review of Endocrinology & MetabolismRequires access
Desmopressin acetate for enuresis and diabetes insipidus
Ormella Cuomo, Lucia Tafuro, Roberto Del Gado
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Abstract
Desmopressin is a synthetic agonist of the natural pituitary hormone vasopressin acetate, with enhanced antidiuretic properties. In fact, owing to its selectivity for the V2 receptor, it has a greater antidiuretic activity, but lower pressure effects compared with natural antidiuretic hormone. Desmopressin is used in the diagnosis and treatment of cranial diabetes insipidus, in the treatment of monosymptomatic enuresis and for tests of renal function.