Oral anticoagulants in the management of thromboembolism
Kate Woodrow, Nicola Korn
Abstract
Kate Woodrow, Nicola Korn
Abstract
Venous thromboembolism presents a major public health concern in the UK, and increases morbidity and mortality in hospitalized patients. With the development of two new classes of oral anticoagulants, direct thrombin inhibitors (dabigatran) and direct factor Xa inhibitors (rivaroxaban), there could be a paradigm shift in the management of acute venous thromboembolism.
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Venous thromboembolism presents a major public health concern in the UK, and increases morbidity and mortality in hospitalized patients. With the development of two new classes of oral anticoagulants, direct thrombin inhibitors (dabigatran) and direct factor Xa inhibitors (rivaroxaban), there could be a paradigm shift in the management of acute venous thromboembolism.
Key concepts: Medicine, Rivaroxaban, Dabigatran, Venous thromboembolism, Intensive care medicine, Discovery and development of direct thrombin inhibitors, Direct thrombin inhibitor, Thrombin