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Antitumor and Other Effects of 24R,25-Dihydroxycholecalciferol in Lewis Lung Carcinoma Causing Abnormal Calcium Metabolism in Tumor-Bearing Mice

Yuji Maeda, Hideyuki Yamato, Tohru Hirai, Noriko Kobori, Takayoshi Fujii, Yasuhiko Kobayashi, Ken-ichi SAITOH, Eiji Inoguchi, Michinori Hakozaki, Hiroko Iijima, Tohru Kodaira, Yutaka Konai, Tadaaki Katoh, C Yoshikumi, Yoshio Kawai, Kikuo Nomoto

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Abstract

Lewis lung carcinoma was found to cause hypercalcemia in tumor-bearing mice. 24R,25(OH)2D3 (K-DR, prepared by Kureha Chemical Ind.) significantly prolonged the survival time of mice with Lewis lung carcinoma. K-DR exhibited an antimetastatic effect on Lewis lung carcinoma, and also had an analgesic effect in mice with Lewis lung carcinoma.

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What this paper is about

Lewis lung carcinoma was found to cause hypercalcemia in tumor-bearing mice. 24R,25(OH)2D3 (K-DR, prepared by Kureha Chemical Ind.) significantly prolonged the survival time of mice with Lewis lung carcinoma. K-DR exhibited an antimetastatic effect on Lewis lung carcinoma, and also had an analgesic effect in mice with Lewis lung carcinoma.

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OpenAlex reports 10 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Lewis lung carcinoma was found to cause hypercalcemia in tumor-bearing mice. 24R,25(OH)2D3 (K-DR, prepared by Kureha Chemical Ind.) significantly prolonged the survival time of mice with Lewis lung carcinoma. K-DR exhibited an antimetastatic effect on Lewis lung carcinoma, and also had an analgesic effect in mice with Lewis lung carcinoma.

Key concepts: Lewis lung carcinoma, Carcinoma, Lung, Calcium, Internal medicine, Medicine, Endocrinology, Cancer research

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Antitumor and Other Effects of 24R,25-Dihydroxycholecalciferol in Lewis Lung Carcinoma Causing Abnormal Calcium Metabolism in Tumor-Bearing Mice — Research Paper | ScholarLens