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Inosin‐N(1)‐oxid‐Nucleotide als Komplexbildner. I. Darstellung von Inosin‐N(1)‐oxid und dessen 5′‐Monophosphat aus Adenosin‐N(1)‐oxid und dessen 5'‐Monophosphat durch Desaminierung mit Nitrosylchlorid

Helmut Sigel, Hans Herbert Brintzinger

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Abstract

Abstract The hitherto unknown compounds inosine N(1)‐oxide and inosine N(1)‐oxide 5′‐monophosphate have been synthesized by deamination of adenosine N(1)‐oxide and its monophosphate with nitrosyl chloride in dimethylformamide. This method is also useful for deamination of adenosine, adenosine 5′‐monophosphate and adenosine 5′‐triphosphate.

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What this paper is about

Abstract The hitherto unknown compounds inosine N(1)‐oxide and inosine N(1)‐oxide 5′‐monophosphate have been synthesized by deamination of adenosine N(1)‐oxide and its monophosphate with nitrosyl chloride in dimethylformamide. This method is also useful for deamination of adenosine, adenosine 5′‐monophosphate and adenosine 5′‐triphosphate.

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Available abstract

Abstract The hitherto unknown compounds inosine N(1)‐oxide and inosine N(1)‐oxide 5′‐monophosphate have been synthesized by deamination of adenosine N(1)‐oxide and its monophosphate with nitrosyl chloride in dimethylformamide. This method is also useful for deamination of adenosine, adenosine 5′‐monophosphate and adenosine 5′‐triphosphate.

Key concepts: Chemistry, Deamination, Inosine, Adenosine, Nucleotide, Adenosine monophosphate, Dimethylformamide, Medicinal chemistry

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Inosin‐N(1)‐oxid‐Nucleotide als Komplexbildner. I. Darstellung von Inosin‐N(1)‐oxid und dessen 5′‐Monophosphat aus Adenosin‐N(1)‐oxid und dessen 5'‐Monophosphat durch Desaminierung mit Nitrosylchlorid — Research Paper | ScholarLens