2009Tzu Chi Medical JournalOpen access

Mirtazapine and Bupropion Combined Treatment in Treatment-resistant Depression

Chien‐Han Lai

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Abstract

Treatment-resistant depression is a difficult problem in clinical practice. Evidence for the efficacy of newer antidepressants, such as duloxetine and bupropion, is not yet well established. We present a case of treatment-resistant depression with full recovery where a combination of mirtazapine and bupropion was used after a failed response to combined mirtazapine and duloxetine treatment.

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Treatment-resistant depression is a difficult problem in clinical practice. Evidence for the efficacy of newer antidepressants, such as duloxetine and bupropion, is not yet well established. We present a case of treatment-resistant depression with full recovery where a combination of mirtazapine and bupropion was used after a failed response to combined mirtazapine and duloxetine treatment.

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Available abstract

Treatment-resistant depression is a difficult problem in clinical practice. Evidence for the efficacy of newer antidepressants, such as duloxetine and bupropion, is not yet well established. We present a case of treatment-resistant depression with full recovery where a combination of mirtazapine and bupropion was used after a failed response to combined mirtazapine and duloxetine treatment.

Key concepts: Bupropion, Mirtazapine, Medicine, Duloxetine, Depression (economics), Pharmacology, Psychiatry, Antidepressant

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