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1999•Tetrahedron LettersRequires access

Sequential mono-N-arylation of piperazine nitrogens. Part 1: A simplified method and its application to the preparation of a key N,N′-biaryl piperazine antifungal intermediate

Michael Hepperle, Jeffrey Eckert, Dinesh Gala

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Key concepts: Piperazine, Chemistry, Antifungal, Combinatorial chemistry, Key (lock), Catalysis, Organic chemistry, Medicinal chemistry

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Sequential mono-N-arylation of piperazine nitrogens. Part 1: A simplified method and its application to the preparation of a key N,N′-biaryl piperazine antifungal intermediate — Research Paper | ScholarLens