Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease
Slávka Hamuľaková, Ladislav Janovec, Martina Hrabinová, Pavol Kristián, Kamil Kuča, Mária Baňasová, Ján Imrich
Abstract
Slávka Hamuľaková, Ladislav Janovec, Martina Hrabinová, Pavol Kristián, Kamil Kuča, Mária Baňasová, Ján Imrich
Abstract
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Key concepts: Tacrine, Butyrylcholinesterase, Chemistry, Acetylcholinesterase, Cholinesterase, Dissociation constant, Aché, Stereochemistry