1987•ReproductionOpen access

Gonadal development in Tl6H/X Sxr hermaphrodite mice

Heather B. Ward, Anne Laura Dorinthea McLaren, Terry G. Baker

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Abstract

Sexual development was studied in 25 hermaphrodite mice with the genotype T16H/XSxr. The majority of the animals had a male phenotype similar to that seen in XXSxr males. A few, however, had feminized external genitalia and were classified as females. Examination of the gonads and reproductive tracts of the male hermaphrodites revealed a strong tendency for the left gonad to be more masculine than the right. Most of the gonads in male and female hermaphrodites appeared to be ovaries or testes rather than ovotestes.

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Sexual development was studied in 25 hermaphrodite mice with the genotype T16H/XSxr. The majority of the animals had a male phenotype similar to that seen in XXSxr males. A few, however, had feminized external genitalia and were classified as females. Examination of the gonads and reproductive tracts of the male hermaphrodites revealed a strong tendency for the left gonad to be more masculine than the right. Most of the gonads in male and female hermaphrodites appeared to be ovaries or testes rather than ovotestes.

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Available abstract

Sexual development was studied in 25 hermaphrodite mice with the genotype T16H/XSxr. The majority of the animals had a male phenotype similar to that seen in XXSxr males. A few, however, had feminized external genitalia and were classified as females. Examination of the gonads and reproductive tracts of the male hermaphrodites revealed a strong tendency for the left gonad to be more masculine than the right. Most of the gonads in male and female hermaphrodites appeared to be ovaries or testes rather than ovotestes.

Key concepts: Hermaphrodite, Gonad, Disorders of sex development, Ovotestis, Biology, Development of the gonads, Sexual differentiation, True hermaphroditism

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