1987•Clinical and Experimental DermatologyRequires access

Short course bifonazole therapy in pityriasis versicolor

Amalia del Palacio Hernanz, Sara López Gómez, L.IGLESIAS DTEZ

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Abstract

Ninety patients were randomly assigned to one of three treatment regimens for pityriasis versicolor consisting of a once daily application of bifonazole 1% solution for a single day, 2 days (day one and day three) or 3 days (day one, day three and day six). Overall clinical cure rates 3 weeks after the end of therapy ranged from 69·9% to 89·9%. Statistical analysis showed a significant difference (p 0·04) in favour of three days therapy at the assessment three weeks and 90 days after the etui of therapy. Short‐term therapy with three applications of bifonazol seems to be effective in most cases of pityriasis versicolor, and needs to be compared against alternative forms of antifungal therapy.

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What this paper is about

Ninety patients were randomly assigned to one of three treatment regimens for pityriasis versicolor consisting of a once daily application of bifonazole 1% solution for a single day, 2 days (day one and day three) or 3 days (day one, day three and day six). Overall clinical cure rates 3 weeks after the end of therapy ranged from 69·9% to 89·9%. Statistical analysis showed a significant difference (p 0·04) in favour of three days therapy at the assessment three weeks and 90 days after the etui of therapy. Short‐term therapy with three applications of bifonazol seems to be effective in most cases of pityriasis versicolor, and needs to be compared against alternative forms of antifungal therapy.

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Available abstract

Ninety patients were randomly assigned to one of three treatment regimens for pityriasis versicolor consisting of a once daily application of bifonazole 1% solution for a single day, 2 days (day one and day three) or 3 days (day one, day three and day six). Overall clinical cure rates 3 weeks after the end of therapy ranged from 69·9% to 89·9%. Statistical analysis showed a significant difference (p 0·04) in favour of three days therapy at the assessment three weeks and 90 days after the etui of therapy. Short‐term therapy with three applications of bifonazol seems to be effective in most cases of pityriasis versicolor, and needs to be compared against alternative forms of antifungal therapy.

Key concepts: Bifonazole, Pityriasis, Medicine, Antifungal, Dermatology, Mycosis, Significant difference, Surgery

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