1980Transactions of the Royal Society of Tropical Medicine and HygieneRequires access

On the longevity and behaviour of microfilariae of Wuchereria bancrofti, Brugia pahangi and Dirofilaria immitis transfused to laboratory rodents

Eberhard Zielke

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Abstract

Microfilariae of Wuchereria bancrofti and Brugia pahangi, which were inoculated into Meriones unguiculatus and Mastomys natalensis respectively, were found in the peripheral blood of the rodents until the ninth day after infection, but no microfilarial periodicity was observed. Microfilariae of W. bancrofti disappeared much faster from the peripheral blood of jirds after reinfection than after the first inoculation. Microfilariae of Dirofilaria immitis inoculated into M. natalensis and laboratory mice were recovered in the peripheral blood until the 17th day after infection and remained infective to mosquitoes. For the first few days the microfilarial periodicity observed in the rodents was similar to that observed in the donor dog, but then reversed.

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What this paper is about

Microfilariae of Wuchereria bancrofti and Brugia pahangi, which were inoculated into Meriones unguiculatus and Mastomys natalensis respectively, were found in the peripheral blood of the rodents until the ninth day after infection, but no microfilarial periodicity was observed. Microfilariae of W. bancrofti disappeared much faster from the peripheral blood of jirds after reinfection than after the first inoculation. Microfilariae of Dirofilaria immitis inoculated into M. natalensis and laboratory mice were recovered in the peripheral blood until the 17th day after infection and remained infective to mosquitoes. For the first few days the microfilarial periodicity observed in the rodents was similar to that observed in the donor dog, but then reversed.

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Available abstract

Microfilariae of Wuchereria bancrofti and Brugia pahangi, which were inoculated into Meriones unguiculatus and Mastomys natalensis respectively, were found in the peripheral blood of the rodents until the ninth day after infection, but no microfilarial periodicity was observed. Microfilariae of W. bancrofti disappeared much faster from the peripheral blood of jirds after reinfection than after the first inoculation. Microfilariae of Dirofilaria immitis inoculated into M. natalensis and laboratory mice were recovered in the peripheral blood until the 17th day after infection and remained infective to mosquitoes. For the first few days the microfilarial periodicity observed in the rodents was similar to that observed in the donor dog, but then reversed.

Key concepts: Dirofilaria immitis, Brugia pahangi, Wuchereria bancrofti, Microfilaria, Filariasis, Biology, Mastomys, Helminths

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On the longevity and behaviour of microfilariae of Wuchereria bancrofti, Brugia pahangi and Dirofilaria immitis transfused to laboratory rodents — Research Paper | ScholarLens