1974•Acta Medica ScandinavicaRequires access

SUCCESSFUL IMMUNOSUPPRESSIVE TREATMENT OF OLIGURIC EXTRACAPILLARY GLOMERULONEPHRITIS

Herluf Jensen, Klaus Ølgaard, Poul Faarup

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Abstract

Abstract. Ten consecutive patients with oliguric extracapillary glomerulonephritis have been treated with prednisone and/or azathioprine. Six patients responded favourably to the treatment, while 4 died of uraemia. Of the 6 responders 5 were treated with prednisone and azathioprine and one with prednisone. The 6 patients are still on immunosuppressive treatment and have creatinine clearances of 21–75 tnl/min 2–43 months after start of treatment. Thus treatment with prednisone and azathioprine seems to improve the prognosis of oliguric extracapillary glomerulonephritis.

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What this paper is about

Abstract. Ten consecutive patients with oliguric extracapillary glomerulonephritis have been treated with prednisone and/or azathioprine. Six patients responded favourably to the treatment, while 4 died of uraemia. Of the 6 responders 5 were treated with prednisone and azathioprine and one with prednisone. The 6 patients are still on immunosuppressive treatment and have creatinine clearances of 21–75 tnl/min 2–43 months after start of treatment. Thus treatment with prednisone and azathioprine seems to improve the prognosis of oliguric extracapillary glomerulonephritis.

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Available abstract

Abstract. Ten consecutive patients with oliguric extracapillary glomerulonephritis have been treated with prednisone and/or azathioprine. Six patients responded favourably to the treatment, while 4 died of uraemia. Of the 6 responders 5 were treated with prednisone and azathioprine and one with prednisone. The 6 patients are still on immunosuppressive treatment and have creatinine clearances of 21–75 tnl/min 2–43 months after start of treatment. Thus treatment with prednisone and azathioprine seems to improve the prognosis of oliguric extracapillary glomerulonephritis.

Key concepts: Prednisone, Azathioprine, Medicine, Glomerulonephritis, Gastroenterology, Creatinine, Internal medicine, Rapidly progressive glomerulonephritis

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