SUCCESSFUL IMMUNOSUPPRESSIVE TREATMENT OF OLIGURIC EXTRACAPILLARY GLOMERULONEPHRITIS
Herluf Jensen, Klaus Ølgaard, Poul Faarup
Abstract
Herluf Jensen, Klaus Ølgaard, Poul Faarup
Abstract
Abstract. Ten consecutive patients with oliguric extracapillary glomerulonephritis have been treated with prednisone and/or azathioprine. Six patients responded favourably to the treatment, while 4 died of uraemia. Of the 6 responders 5 were treated with prednisone and azathioprine and one with prednisone. The 6 patients are still on immunosuppressive treatment and have creatinine clearances of 21–75 tnl/min 2–43 months after start of treatment. Thus treatment with prednisone and azathioprine seems to improve the prognosis of oliguric extracapillary glomerulonephritis.
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Abstract. Ten consecutive patients with oliguric extracapillary glomerulonephritis have been treated with prednisone and/or azathioprine. Six patients responded favourably to the treatment, while 4 died of uraemia. Of the 6 responders 5 were treated with prednisone and azathioprine and one with prednisone. The 6 patients are still on immunosuppressive treatment and have creatinine clearances of 21–75 tnl/min 2–43 months after start of treatment. Thus treatment with prednisone and azathioprine seems to improve the prognosis of oliguric extracapillary glomerulonephritis.
Key concepts: Prednisone, Azathioprine, Medicine, Glomerulonephritis, Gastroenterology, Creatinine, Internal medicine, Rapidly progressive glomerulonephritis