Flora distribution and drug resistance in catheter-associated urinary tract infection

To investigate flora distribution and drug resistance in catheter-associated urinary tract infection. From January 2003 to January 2008 1,567 patients with urinary tract infection associated with the use of indwelling urinary catheters were analyzed retrospectively, whose urine specimens were cultured for bacteria and the isolated pathogens were tested for drug sensitivity by Kirby-Baue method. 376 pathogens were isolated from the 1,567 urine specimens (24·0%), most of which were Gram-negative bacteria. The extended spectrum β-lactamase (ESBL) rate was 59·8% (79/132) for Escherichia coli and 47·4% (18/38) for Klebsiella pnuemoniae. The isolating rate of Methcillin-resistant Staphylococcus aureus and Methcillin-resistant Staphylococcus epidermidis was 54·7% and 88·2% respectively. Catheter-associated urinary tract infection is mainly caused by Gram-negative bacteria of multi-drug resistance. Use of antibiotics should be based on drug sensitivity tests.