2012•Critical Reviews in Food Science and NutritionRequires access

Polysaccharides in Lentinus edodes : Isolation, Structure, Immunomodulating Activity and Future Prospective

Xiaofei Xu, Huidan Yan, Jian Tang, Jian Chen, Xuewu Zhang

Abstract

Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes. In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extraction and purification methods, chemical structure and chain conformation, the effects on innate and adaptive immunity and their mechanism, relationship between structure and function, and the future prospects.

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Key concepts: Lentinus, Polysaccharide, Chemistry, Isolation (microbiology), Biochemistry, Food science, Biology, Microbiology