2005•Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIERequires access
Plasmonic nanorainbow for label-free biomolecule sensing
Gang L. Liu, Erik H. Anderson, J. Alexander Liddle, Luke P. Lee
Open publisher page 2 citations
Abstract
A gold nanowire array that we call nanorainbow SPR sensor array can be chemically functionalized and used to capture biomolecules. The localized plasmon resonance wavelength of the gold nanowires shifts on the biomolecule binding and reaction sites. The plasmon resonance shift of the gold nanorainbow is sensitive to the biomolecule immobilization in sub-nM concentration. As an application example, label-free oligonucleotide hybridizations are detected on the nanorainbow sensor in a multiplexed microfluidic chip.