Selective Reactions in the Solid State and Organic Solid-Solid Reactions

Since guest molecules in a host-guest complex are arranged regularly and are packed closely, reaction of the guest in the complex is expected to proceed selectively and efficiently in the solid state. When the host compound is chiral, reaction of the guest would proceed enantioselectively. Some such reactions were studied. Furthermore, some usual organic reactions were found to proceed in the solid state. In some cases, organic solid state reactions proceeded more selectively and much faster than in solution. Such solid-solid reactions were also investigated.