2001Laboratory InvestigationOpen access

Apolipoprotein E Protects against Neuropathology Induced by a High-Fat Diet and Maintains the Integrity of the Blood-Brain Barrier during Aging

Monique T. Mulder, Arjan Blokland, Dirk‐Jan van den Berg, Henny Schulten, Arjen H. F. Bakker, Dick Terwel, Wiel M.M. Honig, E. R. de Kloet, Louis M. Havekes, Harry W.M. Steinbusch, Elizabeth C. M. de Lange

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Key concepts: Apolipoprotein E, Knockout mouse, Neuropathology, Blood–brain barrier, Endocrinology, Genetically modified mouse, Internal medicine, Neurodegeneration

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Apolipoprotein E Protects against Neuropathology Induced by a High-Fat Diet and Maintains the Integrity of the Blood-Brain Barrier during Aging — Research Paper | ScholarLens