ScholarLens Back to search
1986•Chemistry LettersRequires access

A NOVEL DECARBOXYLATION OF α-AMINO ACIDS. A FACILE METHOD OF DECARBOXYLATION BY THE USE OF 2-CYCLOHEXEN-1-ONE AS A CATALYST

Mitsunori Hashimoto, Yutaka Eda, Yasutomo Osanai, Toshiaki Iwai, Seiichi Aoki

Open publisher page 67 citations

Abstract

Abstract In the presence of a catalytic amount of 2-cyclohexen-1-one, decarboxylation of α-amino acids proceeds smoothly and affords the corresponding amino compounds in good yields. Optically active amino compounds, (3R)-(−)-3-hydroxypyrrolidine and (2R)-(−)-2-hydroxypropylamine are obtained in 93% and 80% yields, respectively.

About this research paper

What this paper is about

Abstract In the presence of a catalytic amount of 2-cyclohexen-1-one, decarboxylation of α-amino acids proceeds smoothly and affords the corresponding amino compounds in good yields. Optically active amino compounds, (3R)-(−)-3-hydroxypyrrolidine and (2R)-(−)-2-hydroxypropylamine are obtained in 93% and 80% yields, respectively.

Why it matters

OpenAlex reports 67 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract In the presence of a catalytic amount of 2-cyclohexen-1-one, decarboxylation of α-amino acids proceeds smoothly and affords the corresponding amino compounds in good yields. Optically active amino compounds, (3R)-(−)-3-hydroxypyrrolidine and (2R)-(−)-2-hydroxypropylamine are obtained in 93% and 80% yields, respectively.

Key concepts: Decarboxylation, Chemistry, Amino acid, Catalysis, Organic chemistry, Biochemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
A NOVEL DECARBOXYLATION OF α-AMINO ACIDS. A FACILE METHOD OF DECARBOXYLATION BY THE USE OF 2-CYCLOHEXEN-1-ONE AS A CATALYST — Research Paper | ScholarLens