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Detection of the PML/RARα fusion gene in acute promyelocytic leukemia with a complex translocation involving chromosomes 15, 17, and 18

Seishi Ogawa, Kinuko Mitani, Yuko Sato, Kouichi Sugimoto, Hideo Toyoshima, Hiroyuki Mano, Fumimaro Takaku, Y Yazaki, Hisamaru Hirai

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Key concepts: Acute promyelocytic leukemia, Biology, Chromosomal translocation, Promyelocytic leukemia protein, Fusion gene, Southern blot, Polymerase chain reaction, Molecular biology

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Detection of the PML/RARα fusion gene in acute promyelocytic leukemia with a complex translocation involving chromosomes 15, 17, and 18 — Research Paper | ScholarLens