2009•Acta Neurologica ScandinavicaRequires access

Central pontine myelinolysis A case report with typical neuropathological findings

A Kold, O. J. Johansen, Ingermarie Reintoft, Edith Reske‐Nielsen

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Abstract

A case of central pontine myelinolysis (CPM) in an alcoholic patient with severe electrolyte changes is presented. Data in the literature suggest that it is safe to correct severe symptomatic hyponatremia to a value of 125-130 mEq/1 in 24 h. At the present time acute severe hyponatremia carries a bad prognosis if not treated with hypertonic NaCl solution. Electrolyte abnormalities are not the sole cause of CPM.

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What this paper is about

A case of central pontine myelinolysis (CPM) in an alcoholic patient with severe electrolyte changes is presented. Data in the literature suggest that it is safe to correct severe symptomatic hyponatremia to a value of 125-130 mEq/1 in 24 h. At the present time acute severe hyponatremia carries a bad prognosis if not treated with hypertonic NaCl solution. Electrolyte abnormalities are not the sole cause of CPM.

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OpenAlex reports 4 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A case of central pontine myelinolysis (CPM) in an alcoholic patient with severe electrolyte changes is presented. Data in the literature suggest that it is safe to correct severe symptomatic hyponatremia to a value of 125-130 mEq/1 in 24 h. At the present time acute severe hyponatremia carries a bad prognosis if not treated with hypertonic NaCl solution. Electrolyte abnormalities are not the sole cause of CPM.

Key concepts: Central pontine myelinolysis, Hyponatremia, Electrolyte imbalance, Electrolyte Disorder, Medicine, Tonicity, Internal medicine

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