Etiologic Studies of Trachoma on Taiwan.
J. Thomas Grayston, S.-p. Wang, Paul B. Johnston
Abstract
J. Thomas Grayston, S.-p. Wang, Paul B. Johnston
Abstract
Eye specimens from first grade school children on Taiwan were cultured in yolk sac of embryonated chicken eggs and in HeLa cell tissue cultures. Four viruses, morphologically and serologically related to psittacosis-lymphogranuloma venereum group, were isolated in yolk sac from 32 children with stage II trachoma, while negative results were obtained with similar cultures of 68 specimens from other stages of trachoma, conjunctivitis and uninfected eyes. These viruses are thought to be etiologic agents of trachoma. One adenovirus was isolated from 468 children with trachoma and 4 adenoviruses were isolated from 375 children with chronic conjunctivitis. Within limitation of age group studied, it is concluded that adenoviruses do not play an important role in trachoma syndrome on Taiwan.
OpenAlex reports 12 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Eye specimens from first grade school children on Taiwan were cultured in yolk sac of embryonated chicken eggs and in HeLa cell tissue cultures. Four viruses, morphologically and serologically related to psittacosis-lymphogranuloma venereum group, were isolated in yolk sac from 32 children with stage II trachoma, while negative results were obtained with similar cultures of 68 specimens from other stages of trachoma, conjunctivitis and uninfected eyes. These viruses are thought to be etiologic agents of trachoma. One adenovirus was isolated from 468 children with trachoma and 4 adenoviruses were isolated from 375 children with chronic conjunctivitis. Within limitation of age group studied, it is concluded that adenoviruses do not play an important role in trachoma syndrome on Taiwan.
Key concepts: Trachoma, Embryonated, Lymphogranuloma venereum, Psittacosis, Chlamydia trachomatis, Yolk sac, Chlamydia, Virology