microRNA and protein expression in breast cancer formalin-fixed paraffin-embedded samples

microRNAs (miRNAs) constitute a new class of small noncoding RNAs that control post-transcriptionally the expression of gene products, either modulating directly protein translation or regulating the stability of messenger RNA. There is increasing evidence of the role that miRNAs play in regulating breast cancer gene expression. The main objective of this study is to evaluate the diagnostic utility of the expression of a panel of miRNAs in breast cancer and compare their expression with the expression of the proteins they regulate.