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Coincident cytomegalovirus infection and toxoplasmosis in an uncompromised host.

K. G. Nicholson

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Abstract

Coincident cytomegalovirus infection and toxoplasmosis in an uncompromised hostSimultaneous infection by the obligate intracellular parasite Toxo- plasma gondii and by cytomegalovirus has been described in stillborn infants with congenitally acquired diseasel 2 and occurs with an unexpected frequency in patients with disseminated neoplasia.34 Under normal circumstances it is uncommon for either agent to cause overt disease, and coincident infection with T gondii and cytomegalovirus does not appear to have been described in an otherwise healthy adult.I present a case of atypical mononucleosis accompanied by serological evidence of infection with both agents.Case report A 71-year-old Welsh hill farmer was admitted three weeks after the onset of chills, lassitude, anorexia, occasional vomiting, and episodes of irrational behaviour.Apart from fever of 38°C there were no abnormal physical signs.Haemoglobin concentration was 13 8 g/dl with normal blood variables.Serum sodium and potassium concentrations were low at 131 mmol(mEq)/l

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Coincident cytomegalovirus infection and toxoplasmosis in an uncompromised hostSimultaneous infection by the obligate intracellular parasite Toxo- plasma gondii and by cytomegalovirus has been described in stillborn infants with congenitally acquired diseasel 2 and occurs with an unexpected frequency in patients with disseminated neoplasia.34 Under normal circumstances it is uncommon for either agent to cause overt disease, and coincident infection with T gondii and cytomegalovirus does not appear to have been described in an otherwise healthy adult.I present a case of atypical mononucleosis accompanied by serological evidence of infection with both agents.Case report A 71-year-old Welsh hill farmer was admitted three weeks after the onset of chills, lassitude, anorexia, occasional vomiting, and episodes of irrational behaviour.Apart from fever of 38°C there were no abnormal physical signs.Haemoglobin concentration was 13 8 g/dl with normal blood variables.Serum sodium and potassium concentrations were low at 131 mmol(mEq)/l

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Available abstract

Coincident cytomegalovirus infection and toxoplasmosis in an uncompromised hostSimultaneous infection by the obligate intracellular parasite Toxo- plasma gondii and by cytomegalovirus has been described in stillborn infants with congenitally acquired diseasel 2 and occurs with an unexpected frequency in patients with disseminated neoplasia.34 Under normal circumstances it is uncommon for either agent to cause overt disease, and coincident infection with T gondii and cytomegalovirus does not appear to have been described in an otherwise healthy adult.I present a case of atypical mononucleosis accompanied by serological evidence of infection with both agents.Case report A 71-year-old Welsh hill farmer was admitted three weeks after the onset of chills, lassitude, anorexia, occasional vomiting, and episodes of irrational behaviour.Apart from fever of 38°C there were no abnormal physical signs.Haemoglobin concentration was 13 8 g/dl with normal blood variables.Serum sodium and potassium concentrations were low at 131 mmol(mEq)/l

Key concepts: Toxoplasmosis, Virology, Cytomegalovirus, Cytomegalovirus infection, Host (biology), Medicine, Biology, Human cytomegalovirus

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