Combining direct methods with isomorphous replacement or anomalous scattering data. V. Comparison of different phasing methods in the OAS case
QIAN JIN-ZI, Hai-fu Fan, Yuan-Xin Gu
Abstract
QIAN JIN-ZI, Hai-fu Fan, Yuan-Xin Gu
Abstract
Different methods for resolving the phase ambiguity resulting from the OAS (one-wavelength anomalous scattering) technique are compared in the application to two model protein structures. It is concluded that the information from both Sim's and Cochran's distributions is valuable in separating the phase doublets. However, the combination of Sim's and Cochran's distributions can lead to a better result than that obtainable by using either alone.
OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Different methods for resolving the phase ambiguity resulting from the OAS (one-wavelength anomalous scattering) technique are compared in the application to two model protein structures. It is concluded that the information from both Sim's and Cochran's distributions is valuable in separating the phase doublets. However, the combination of Sim's and Cochran's distributions can lead to a better result than that obtainable by using either alone.
Key concepts: Phaser, Anomalous scattering, Scattering, Ambiguity, Wavelength, Phase (matter), Physics, Algorithm