1985•Acta Crystallographica Section A Foundations of CrystallographyRequires access

Combining direct methods with isomorphous replacement or anomalous scattering data. V. Comparison of different phasing methods in the OAS case

QIAN JIN-ZI, Hai-fu Fan, Yuan-Xin Gu

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Abstract

Different methods for resolving the phase ambiguity resulting from the OAS (one-wavelength anomalous scattering) technique are compared in the application to two model protein structures. It is concluded that the information from both Sim's and Cochran's distributions is valuable in separating the phase doublets. However, the combination of Sim's and Cochran's distributions can lead to a better result than that obtainable by using either alone.

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What this paper is about

Different methods for resolving the phase ambiguity resulting from the OAS (one-wavelength anomalous scattering) technique are compared in the application to two model protein structures. It is concluded that the information from both Sim's and Cochran's distributions is valuable in separating the phase doublets. However, the combination of Sim's and Cochran's distributions can lead to a better result than that obtainable by using either alone.

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Available abstract

Different methods for resolving the phase ambiguity resulting from the OAS (one-wavelength anomalous scattering) technique are compared in the application to two model protein structures. It is concluded that the information from both Sim's and Cochran's distributions is valuable in separating the phase doublets. However, the combination of Sim's and Cochran's distributions can lead to a better result than that obtainable by using either alone.

Key concepts: Phaser, Anomalous scattering, Scattering, Ambiguity, Wavelength, Phase (matter), Physics, Algorithm

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