2008•Zeitschrift für Naturforschung COpen access

Biotransformation of Indole Derivatives by Mycelial Cultures

Julio Alarcón, Eliseo Cid, Luis Lillo, Carlos L. Céspedes, Sergio A. Águila, Joel B. Alderete

Abstract

Biotransformation of tryptophan to tryptamine and 3-methyl-indole by Psilocybe coprophila was performed. On the other hand, Aspergillus niger was able to transform tryptophan to 5-hydroxy-tryptophan. P. coprophila biotransformed 5-hydroxy-tryptophan to 5-hydroxytryptamine. These results prove once more that fungi are good tools to establish hydroxyindole derivatives.

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Key concepts: Tryptamine, Biotransformation, Indole test, Tryptophan, Mycelium, Chemistry, Aspergillus niger, Tryptophan Metabolism