Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
Edwina C. Lerner, Tingting Zhang, David B. Knowles, Yimin Qian, Andrew D. Hamilton, Saı̈d M. Sebti
Abstract