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1969•Acta Medica ScandinavicaRequires access

AN IN VITRO DEMONSTRATION OF CELLULAR IMMUNITY AGAINST AUTOLOGOUS MAMMARY CARCINOMA IN MAN

Vibeke Charlotte Andersen, G Bendixen, Torben Schiødt

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Abstract

Abstract In five out of eight patients operated on for mammary carcinoma, an extract of the autologous tumour induced inhibition of the in vitro leukocyte migration. Extracts of the patient's normal mammary tissue gave no inhibition, and negative results were likewise obtained when leukocytes from matched controls were exposed to extracts of isogeneic normal or tumourous tissue. These observations suggest that in some patients mammary carcinoma is associated with a state of cellular hypersensitivity against components of the tumour.

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What this paper is about

Abstract In five out of eight patients operated on for mammary carcinoma, an extract of the autologous tumour induced inhibition of the in vitro leukocyte migration. Extracts of the patient's normal mammary tissue gave no inhibition, and negative results were likewise obtained when leukocytes from matched controls were exposed to extracts of isogeneic normal or tumourous tissue. These observations suggest that in some patients mammary carcinoma is associated with a state of cellular hypersensitivity against components of the tumour.

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OpenAlex reports 57 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Abstract In five out of eight patients operated on for mammary carcinoma, an extract of the autologous tumour induced inhibition of the in vitro leukocyte migration. Extracts of the patient's normal mammary tissue gave no inhibition, and negative results were likewise obtained when leukocytes from matched controls were exposed to extracts of isogeneic normal or tumourous tissue. These observations suggest that in some patients mammary carcinoma is associated with a state of cellular hypersensitivity against components of the tumour.

Key concepts: Mammary carcinoma, In vitro, Medicine, Mammary tissue, Immunity, Carcinoma, Cellular immunity, Delayed hypersensitivity

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AN IN VITRO DEMONSTRATION OF CELLULAR IMMUNITY AGAINST AUTOLOGOUS MAMMARY CARCINOMA IN MAN — Research Paper | ScholarLens