Anticoagulation in Nonvalvular Atrial Fibrillation
Bipinpreet S. Nagra, Bharat K. Kantharia
Abstract
Bipinpreet S. Nagra, Bharat K. Kantharia
Abstract
Atrial fibrillation is the most common, serious, cardiac arrhythmia and increases the risk for ischemic stroke fivefold. Nonvalvular atrial fibrillation may be responsible for up to 15-20% of strokes. Antiplatelet agents and oral anticoagulants are used for stroke prevention in atrial fibrillation. The following review article discusses the potential risks and benefits of oral anticoagulants in nonvalvular atrial fibrillation with particular emphasis on accurate risk stratification tools for ischemic stroke.
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Atrial fibrillation is the most common, serious, cardiac arrhythmia and increases the risk for ischemic stroke fivefold. Nonvalvular atrial fibrillation may be responsible for up to 15-20% of strokes. Antiplatelet agents and oral anticoagulants are used for stroke prevention in atrial fibrillation. The following review article discusses the potential risks and benefits of oral anticoagulants in nonvalvular atrial fibrillation with particular emphasis on accurate risk stratification tools for ischemic stroke.
Key concepts: Medicine, Atrial fibrillation, Cardiology, Stroke (engine), Internal medicine, Risk stratification, Ischemic stroke, Stroke risk