Synthetic lethality of PARP inhibitors and metformin in BRCA1 intact ovarian cancer
Miriana Hijaz, Jasdeep Chhina, Sajad Ahmad Dar, Calvin Tebbe, Zaid Al-Wahab, Rabbie K. Hanna, Ramandeep Rattan, Adnan Munkarah
Abstract
Miriana Hijaz, Jasdeep Chhina, Sajad Ahmad Dar, Calvin Tebbe, Zaid Al-Wahab, Rabbie K. Hanna, Ramandeep Rattan, Adnan Munkarah
Abstract
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Key concepts: Synthetic lethality, Poly ADP ribose polymerase, Metformin, Medicine, Ovarian cancer, PARP inhibitor, Olaparib, Lethality