ScholarLens Back to search
1998•Canadian Journal of Animal ScienceRequires access

Dose-response of injected recombinant porcine prolactin on concentrations of prolactin in lactating sows

S. Horth, Jean-Paul Laforest, C. Farmer

Open publisher page 3 citations

Abstract

HBlood profiles of prolactin (PRL) were obtained in sows after receiving a s.c. injection of 0 mg (n = 7), 5 mg (n = 10), or 15 mg (n = 9) of recombinant porcine prolactin (pPRL) on days 6 and 20 of lactation. The 15-mg dose of pPRL increased PRL concentrations (P ≤ 0.01) from 15 min to 11 h post-injection at both 6 and 20 d of lactation, whereas a sustained increase in PRL (P ≤ 0.05) following the 5-mg dose was seen on day 20 only, and lasted from 1 to 7 h post-injection. The results demonstrate that stage of lactation, as well as dose and time since PRL injection affect the PRL response of lactating sows to exogenous pPRL. Key words: Sow, lactation, prolactin, injection

About this research paper

What this paper is about

HBlood profiles of prolactin (PRL) were obtained in sows after receiving a s.c. injection of 0 mg (n = 7), 5 mg (n = 10), or 15 mg (n = 9) of recombinant porcine prolactin (pPRL) on days 6 and 20 of lactation. The 15-mg dose of pPRL increased PRL concentrations (P ≤ 0.01) from 15 min to 11 h post-injection at both 6 and 20 d of lactation, whereas a sustained increase in PRL (P ≤ 0.05) following the 5-mg dose was seen on day 20 only, and lasted from 1 to 7 h post-injection. The results demonstrate that stage of lactation, as well as dose and time since PRL injection affect the PRL response of lactating sows to exogenous pPRL. Key words: Sow, lactation, prolactin, injection

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

HBlood profiles of prolactin (PRL) were obtained in sows after receiving a s.c. injection of 0 mg (n = 7), 5 mg (n = 10), or 15 mg (n = 9) of recombinant porcine prolactin (pPRL) on days 6 and 20 of lactation. The 15-mg dose of pPRL increased PRL concentrations (P ≤ 0.01) from 15 min to 11 h post-injection at both 6 and 20 d of lactation, whereas a sustained increase in PRL (P ≤ 0.05) following the 5-mg dose was seen on day 20 only, and lasted from 1 to 7 h post-injection. The results demonstrate that stage of lactation, as well as dose and time since PRL injection affect the PRL response of lactating sows to exogenous pPRL. Key words: Sow, lactation, prolactin, injection

Key concepts: Prolactin, Lactation, Internal medicine, Endocrinology, Recombinant DNA, Chemistry, Biology, Animal science

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Dose-response of injected recombinant porcine prolactin on concentrations of prolactin in lactating sows — Research Paper | ScholarLens