1980Journal of Environmental Science and Health Part BRequires access

Effect of polychlorinated biphenyl, dibenzofuran and dibenzo‐p‐dioxin on the susceptibility of male mice to endotoxin

Shogo Oishi, K. Hiraga

Open publisher page 8 citations

Abstract

The effect of polychlorinated biphenyl (PCB), dibenzofuran (CDF) and dibenzo-p-dioxin (CDD) on endotoxin sensitivity was studied in male mice. The oral administration of CDF and CDD, once a week for 4 weeks, increased endotoxin sensitivity, whereas, PCB was not affective. On the other hand, residual levels of PCB were detected in thymus but CDF and CDD were not.

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What this paper is about

The effect of polychlorinated biphenyl (PCB), dibenzofuran (CDF) and dibenzo-p-dioxin (CDD) on endotoxin sensitivity was studied in male mice. The oral administration of CDF and CDD, once a week for 4 weeks, increased endotoxin sensitivity, whereas, PCB was not affective. On the other hand, residual levels of PCB were detected in thymus but CDF and CDD were not.

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Available abstract

The effect of polychlorinated biphenyl (PCB), dibenzofuran (CDF) and dibenzo-p-dioxin (CDD) on endotoxin sensitivity was studied in male mice. The oral administration of CDF and CDD, once a week for 4 weeks, increased endotoxin sensitivity, whereas, PCB was not affective. On the other hand, residual levels of PCB were detected in thymus but CDF and CDD were not.

Key concepts: Dibenzofuran, Polychlorinated biphenyl, Biphenyl, Chemistry, Internal medicine, Pharmacology, Toxicology, Environmental chemistry

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Effect of polychlorinated biphenyl, dibenzofuran and dibenzo‐p‐dioxin on the susceptibility of male mice to endotoxin — Research Paper | ScholarLens