The role of the sympathetic nervous system in atropine-induced tachycardia in conscious cats
Г. Е. Самонина, M. O. K. Hakumäki
Abstract
Г. Е. Самонина, M. O. K. Hakumäki
Abstract
Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.
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Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.
Key concepts: Atropine, CATS, Tachycardia, Muscarinic acetylcholine receptor, Medicine, Sympathetic nervous system, Anesthesia, Parasympathetic nervous system