1983Scandinavian Journal of Clinical and Laboratory InvestigationRequires access

The role of the sympathetic nervous system in atropine-induced tachycardia in conscious cats

Г. Е. Самонина, M. O. K. Hakumäki

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Abstract

Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.

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What this paper is about

Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.

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Available abstract

Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.

Key concepts: Atropine, CATS, Tachycardia, Muscarinic acetylcholine receptor, Medicine, Sympathetic nervous system, Anesthesia, Parasympathetic nervous system

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