1993Journal of NeurobiologyRequires access

Members of the Dlx‐and NKx2‐gene families are regionally expressed in the developing forebrain

Melanie Price

Open publisher page 64 citations

Abstract

Members of the vertebrate Dlx- and Nkx2-homeobox-containing gene families exhibit closely related, complementary areas of gene expression in the developing forebrain. The expression domains and onset of gene transcription indicate that these genes may play a role in forebrain patterning, particularly in the diencephalon. In some cases, gene expression borders coincide with morphological boundaries separating functional and anatomical regions of the forebrain suggesting that the rostral region of the neural tube may indeed arise frm a segmented structure.

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What this paper is about

Members of the vertebrate Dlx- and Nkx2-homeobox-containing gene families exhibit closely related, complementary areas of gene expression in the developing forebrain. The expression domains and onset of gene transcription indicate that these genes may play a role in forebrain patterning, particularly in the diencephalon. In some cases, gene expression borders coincide with morphological boundaries separating functional and anatomical regions of the forebrain suggesting that the rostral region of the neural tube may indeed arise frm a segmented structure.

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Available abstract

Members of the vertebrate Dlx- and Nkx2-homeobox-containing gene families exhibit closely related, complementary areas of gene expression in the developing forebrain. The expression domains and onset of gene transcription indicate that these genes may play a role in forebrain patterning, particularly in the diencephalon. In some cases, gene expression borders coincide with morphological boundaries separating functional and anatomical regions of the forebrain suggesting that the rostral region of the neural tube may indeed arise frm a segmented structure.

Key concepts: Forebrain, Biology, Gene, Neuroscience, Evolutionary biology, Gene family, Genetics, Gene expression

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