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2008•Bioorganic & Medicinal Chemistry LettersRequires access

Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site

Vladimir Torbeev, Kalyaneswar Mandal, Valentina A. Terechko, Stephen B. H. Kent

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Key concepts: Isostere, Chemistry, Stereochemistry, HIV-1 protease, Enzyme inhibitor, Protease, Enzyme, Protease inhibitor (pharmacology)

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Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site — Research Paper | ScholarLens