2002Chinese Journal of ChemistryRequires access

Study on the Model for Regulation of the Allosteric Enzyme Activity

Qian‐Zhong Li, Liaofu Luo, Lirong Zhang

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Abstract

Abstract The effects of activator molecule and repressive molecule on binding process between allosteric enzyme and substrate are discussed by considering the heterotropic effect of the regulating molecule that binds to allosteric enzyme. A model of allosteric enzyme with heterotropic effect is presented. The cooperativity and anticooperativity in the regulation process are studied.

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What this paper is about

Abstract The effects of activator molecule and repressive molecule on binding process between allosteric enzyme and substrate are discussed by considering the heterotropic effect of the regulating molecule that binds to allosteric enzyme. A model of allosteric enzyme with heterotropic effect is presented. The cooperativity and anticooperativity in the regulation process are studied.

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Available abstract

Abstract The effects of activator molecule and repressive molecule on binding process between allosteric enzyme and substrate are discussed by considering the heterotropic effect of the regulating molecule that binds to allosteric enzyme. A model of allosteric enzyme with heterotropic effect is presented. The cooperativity and anticooperativity in the regulation process are studied.

Key concepts: Allosteric regulation, Cooperativity, Chemistry, Allosteric enzyme, Enzyme, Cooperative binding, Molecule, Enzyme activator

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